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LHON viral vector treatment trial started
IFOND scientific members, coordinating with colleagues in North America and Europe, are involved in human LHON 11778 viral vector treatment trials using technology pioneered by Dr. John Guy's team at Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine in Miami Florida. See: Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE), and www.gensight-biologics.com for further information. Note this interesting Chinese safety and efficacy open study: Wan et al. Efficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy. Sci Rep. 2016; 6: 21587. Also at http://www.nature.com/articles/srep21587
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